My take on all of these additives, slick-50, teflon, super snake oil, etc. is that if any of them really made some significant difference there would be good data to support their use. Maybe they do improve mileage; maybe they do decrease engine wear. But who's to say that they don't do the opposite, they just dilute otherwise perfectly good oil. Or they have no real benefit, do no harm and really amount to an unnecessary expense.
I'll settle for changing the oil reasonably frequently, using good oil, and being real careful not to get grit, grime, dust, or crud into the crankcase during an oil change. (How clean is that funnel?)
I doubt there is any really good research on the stuff, just manufacturer's claims, and personal testimony (which I take with a grain of salt because it is so subjective. Hey, my bike runs smoother and has more power after I change the oil and wash it).
Oh, except Marvel Mystery Oil. Now that is good stuff. Neat paint job on the can. You can add it to the gas tank and put it in the crankcase. Cleans injectors and quiets valves.
I am being a little facetious here, but I do truly have a can of the stuff around here.